VDAC1 selectively transfers apoptotic Ca(2+) signals to mitochondria

Voltage-dependent anion channels (VDACs) are expressed in three isoforms, with common channeling properties and different roles in cell survival. We show that VDAC1 silencing potentiates apoptotic challenges, whereas VDAC2 has the opposite effect. Although all three VDAC isoforms are equivalent in a...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: De Stefani, D, Bononi, A, Romagnoli, A, Messina, A, De Pinto, V, Pinton, P, Rizzuto, R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
Aiheet:
Original Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263501/
https://ncbi.nlm.nih.gov/pubmed/21720385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.92
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