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VDAC1 selectively transfers apoptotic Ca(2+) signals to mitochondria
Voltage-dependent anion channels (VDACs) are expressed in three isoforms, with common channeling properties and different roles in cell survival. We show that VDAC1 silencing potentiates apoptotic challenges, whereas VDAC2 has the opposite effect. Although all three VDAC isoforms are equivalent in a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263501/ https://ncbi.nlm.nih.gov/pubmed/21720385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.92 |
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