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Selective Aurora kinase inhibitors identified using a Taxol-induced checkpoint sensitivity screen
The members of the Aurora kinase family play critical roles in the regulation of the cell cycle and mitotic spindle assembly and have been intensively investigated as potential targets for a new class of anti-cancer drugs. We describe a new highly potent and selective class of Aurora kinase inhibito...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262907/ https://ncbi.nlm.nih.gov/pubmed/21992004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200305u |
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