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Selective Aurora kinase inhibitors identified using a Taxol-induced checkpoint sensitivity screen

The members of the Aurora kinase family play critical roles in the regulation of the cell cycle and mitotic spindle assembly and have been intensively investigated as potential targets for a new class of anti-cancer drugs. We describe a new highly potent and selective class of Aurora kinase inhibito...

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Detaylı Bibliyografya
Asıl Yazarlar: Kwiatkowski, Nicholas, Deng, Xianming, Wang, Jinhua, Tan, Li, Villa, Fabrizio, Santaguida, Stefano, Huang, Hsiao-Chun, Mitchison, Tim, Musacchio, Andrea, Gray, Nathanael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262907/
https://ncbi.nlm.nih.gov/pubmed/21992004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200305u
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