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Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia

The natural history of severe hemoglobinopathies like sickle cell disease (SCD) is rather variable, depending on the circumstances, but the main influence on such variability is the level of fetal hemoglobin (HbF) in the patient’s red cells. It is well known that a significant HbF level is associate...

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Bibliographic Details
Main Authors: Eridani, Sandro, Mosca, Andrea
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262355/
https://ncbi.nlm.nih.gov/pubmed/22287860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S14942
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