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Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia

The natural history of severe hemoglobinopathies like sickle cell disease (SCD) is rather variable, depending on the circumstances, but the main influence on such variability is the level of fetal hemoglobin (HbF) in the patient’s red cells. It is well known that a significant HbF level is associate...

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Библиографические подробности
Главные авторы: Eridani, Sandro, Mosca, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262355/
https://ncbi.nlm.nih.gov/pubmed/22287860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S14942
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