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Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia

The natural history of severe hemoglobinopathies like sickle cell disease (SCD) is rather variable, depending on the circumstances, but the main influence on such variability is the level of fetal hemoglobin (HbF) in the patient’s red cells. It is well known that a significant HbF level is associate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eridani, Sandro, Mosca, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262355/
https://ncbi.nlm.nih.gov/pubmed/22287860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S14942
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