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Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia

The natural history of severe hemoglobinopathies like sickle cell disease (SCD) is rather variable, depending on the circumstances, but the main influence on such variability is the level of fetal hemoglobin (HbF) in the patient’s red cells. It is well known that a significant HbF level is associate...

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Main Authors: Eridani, Sandro, Mosca, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262355/
https://ncbi.nlm.nih.gov/pubmed/22287860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S14942
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