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BNIP3 (Bcl-2 19 kDa Interacting Protein) Acts as Transcriptional Repressor of Apoptosis-Inducing Factor Expression Preventing Cell Death in Human Malignant Gliomas

The Bcl-2 19 kDa interacting protein (BNIP3) is a pro-cell-death BH3-only member of the Bcl-2 family. We previously found that BNIP3 is localized to the nucleus in the majority of glioblastoma multiforme (GBM) tumors and fails to induce cell death. Herein, we have discovered that nuclear BNIP3 binds...

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Библиографические подробности
Главные авторы: Burton, Teralee R., Eisenstat, David D., Gibson, Spencer B.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262017/
https://ncbi.nlm.nih.gov/pubmed/19339613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5747-08.2009
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