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Truncated forms of BNIP3 act as dominant negatives inhibiting hypoxia-induced cell death
BNIP3 (Bcl-2/adenovirus E1B Ninteen Kilodalton Interacting Protein) is a pro-cell death member of the Bcl-2 family of proteins. Its expression is induced by the transcription factor Hypoxia Inducible Factor-1 (HIF-1) under conditions of low oxygen (hypoxia) and is found over expressed in hypoxic reg...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164856/ https://ncbi.nlm.nih.gov/pubmed/21138765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.11.013 |
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