Truncated forms of BNIP3 act as dominant negatives inhibiting hypoxia-induced cell death

BNIP3 (Bcl-2/adenovirus E1B Ninteen Kilodalton Interacting Protein) is a pro-cell death member of the Bcl-2 family of proteins. Its expression is induced by the transcription factor Hypoxia Inducible Factor-1 (HIF-1) under conditions of low oxygen (hypoxia) and is found over expressed in hypoxic reg...

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Autores principales: Bristow, Nicolle, Burton, Teralee R, Henson, Elizabeth S, Ong-Justiniano, Coleen, Brown, Michelle, Gibson, Spencer B
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164856/
https://ncbi.nlm.nih.gov/pubmed/21138765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.11.013
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