BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas

Glioblastoma multiforme (GBM) is the most common and malignant brain tumor, and current treatment modalities such as surgical resection, adjuvant radiotherapy and temozolomide (TMZ) chemotherapy are ineffective. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a novel cancer therap...

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Detalhes bibliográficos
Main Authors: Burton, T R, Henson, E S, Azad, M B, Brown, M, Eisenstat, D D, Gibson, S B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641324/
https://ncbi.nlm.nih.gov/pubmed/23579274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.100
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