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Drug Interactions with Bacillus anthracis Topoisomerase IV: Biochemical Basis for Quinolone Action and Resistance()

Bacillus anthracis, the causative agent of anthrax, is considered a serious threat as a bioweapon. The drugs most commonly used to treat anthrax are quinolones, which act by increasing DNA cleavage mediated by topoisomerase IV and gyrase. Quinolone resistance most often is associated with specific s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Aldred, Katie J., McPherson, Sylvia A., Wang, Pengfei, Kerns, Robert J., Graves, David E., Turnbough, Charles L., Osheroff, Neil
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261753/
https://ncbi.nlm.nih.gov/pubmed/22126453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2013905
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