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An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
Chromosomal translocations arise from the misjoining of DNA breaks, but the identity of the DNA repair factors and activities involved in their formation has been elusive. Here we show that depletion of CtIP, a DNA end-resection factor, results in a substantial decrease in chromosomal translocation...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261752/ https://ncbi.nlm.nih.gov/pubmed/21131978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1940 |
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