Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts

BACKGROUND: Lung fibrosis is characterized by fibroblast proliferation and the deposition of collagens. Curcumin, a polyphenol antioxidant from the spice tumeric, has been shown to effectively counteract fibroblast proliferation and reducing inflammation and fibrotic progression in animal models of...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Dongwei, Huang, Chuangfang, Yang, Changfu, Liu, Renzuo J, Wang, Jifeng, Niu, Jianzhao, Brömme, Dieter
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260240/
https://ncbi.nlm.nih.gov/pubmed/22126332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-154
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