Co-compartmentalization of the Astroglial Glutamate Transporter, GLT-1, with Glycolytic Enzymes and Mitochondria

Efficient excitatory transmission depends on a family of transporters that use the Na(+)-electrochemical gradient to maintain low synaptic concentrations of glutamate. These transporters consume substantial energy in the spatially restricted space of fine astrocytic processes. GLT-1 (EAAT2) mediates...

Full description

Saved in:
Bibliographic Details
Main Authors: Genda, Elizabeth N., Jackson, Joshua G., Sheldon, Amanda L., Locke, Susannah F., Greco, Todd M., O'Donnell, John C., Spruce, Lynn A., Xiao, Rui, Guo, Wensheng, Putt, Mary, Seeholzer, Steven, Ischiropoulos, Harry, Robinson, Michael B.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259858/
https://ncbi.nlm.nih.gov/pubmed/22171032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3305-11.2011
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items