Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo

How the loss of fragile X mental retardation protein (FMRP) in different brain cell types, especially in non-neuron glial cells, induces fragile X syndrome (FXS) phenotypes has just begun to be understood. In the current study, we generated inducible astrocyte-specific Fmr1 conditional knock-out mic...

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Vydáno v:J Neurosci
Hlavní autoři: Higashimori, Haruki, Schin, Christina S., Chiang, Ming Sum R., Morel, Lydie, Shoneye, Temitope A., Nelson, David L., Yang, Yongjie
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938857/
https://ncbi.nlm.nih.gov/pubmed/27383586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1069-16.2016
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