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UBIQUITINATION-MEDIATED INTERNALIZATION AND DEGRADATION OF THE ASTROGLIAL GLUTAMATE TRANSPORTER, GLT-1

Sodium-dependent glutamate uptake is essential for limiting excitotoxicity, and dysregulation of this process has been implicated in a wide array of neurological disorders. The majority of forebrain glutamate uptake is mediated by the astroglial glutamate transporter, GLT-1. We and others have shown...

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Detalhes bibliográficos
Main Authors: Sheldon, Amanda L., González, Marco I., Krizman-Genda, Elizabeth N., Susarla, Bala T.S., Robinson, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629405/
https://ncbi.nlm.nih.gov/pubmed/18805448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2008.07.010
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