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INTERNALIZATION AND DEGRADATION OF THE GLUTAMATE TRANSPORTER GLT-1 IN RESPONSE TO PHORBOL ESTER

Activation of protein kinase C (PKC) decreases the activity and cell surface expression of the predominant forebrain glutamate transporter, GLT-1. In the present study, C6 glioma were used as a model system to define the mechanisms that contribute to this decrease in cell surface expression and to d...

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Autori principali: Susarla, Bala T.S., Robinson, Michael B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292111/
https://ncbi.nlm.nih.gov/pubmed/17919781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2007.08.020
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