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Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT-1 by a Notch-dependent mechanism

Neuron-secreted factors induce astrocytic expression of the glutamate transporter, GLT-1 (EAAT2). In addition to their elaborate anatomic relationships with neurons, astrocytes also have processes that extend to and envelop the vasculature. Although previous studies have demonstrated that brain endo...

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Bibliographic Details
Published in:J Neurochem
Main Authors: Lee, Meredith L., Martinez-Lozada, Zila, Krizman, Elizabeth N., Robinson, Michael B.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693650/
https://ncbi.nlm.nih.gov/pubmed/28771710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14135
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