Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1

Perisynaptic astrocytes express important glutamate transporters, especially excitatory amino acid transporter 2 (EAAT2, rodent analog GLT1) to regulate extracellular glutamate levels and modulate synaptic activation. In this study, we investigated an exciting new pathway, the exosome-mediated trans...

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Detalhes bibliográficos
Main Authors: Morel, Lydie, Regan, Melissa, Higashimori, Haruki, Ng, Seng Kah, Esau, Christine, Vidensky, Svetlana, Rothstein, Jeffrey, Yang, Yongjie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591620/
https://ncbi.nlm.nih.gov/pubmed/23364798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410944
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