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Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1

Perisynaptic astrocytes express important glutamate transporters, especially excitatory amino acid transporter 2 (EAAT2, rodent analog GLT1) to regulate extracellular glutamate levels and modulate synaptic activation. In this study, we investigated an exciting new pathway, the exosome-mediated trans...

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Hlavní autoři: Morel, Lydie, Regan, Melissa, Higashimori, Haruki, Ng, Seng Kah, Esau, Christine, Vidensky, Svetlana, Rothstein, Jeffrey, Yang, Yongjie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591620/
https://ncbi.nlm.nih.gov/pubmed/23364798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410944
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