A Conformationally Mobile Cysteine Residue (Cys-561) Modulates Na(+) and H(+) Activation of Human CNT3

In humans, the SLC28 concentrative nucleoside transporter (CNT) protein family is represented by three Na(+)-coupled members; human CNT1 (hCNT1) and hCNT2 are pyrimidine and purine nucleoside-selective, respectively, whereas hCNT3 transports both purine and pyrimidine nucleosides and nucleoside drug...

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Detalhes bibliográficos
Main Authors: Slugoski, Melissa D., Smith, Kyla M., Mulinta, Ras, Ng, Amy M. L., Yao, Sylvia Y. M., Morrison, Ellen L., Lee, Queenie O. T., Zhang, Jing, Karpinski, Edward, Cass, Carol E., Baldwin, Stephen A., Young, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259814/
https://ncbi.nlm.nih.gov/pubmed/18621735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801793200
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