Conserved Glutamate Residues Glu-343 and Glu-519 Provide Mechanistic Insights into Cation/Nucleoside Cotransport by Human Concentrative Nucleoside Transporter hCNT3

Human concentrative nucleoside transporter 3 (hCNT3) utilizes electrochemical gradients of both Na(+) and H(+) to accumulate pyrimidine and purine nucleosides within cells. We have employed radioisotope flux and electrophysiological techniques in combination with site-directed mutagenesis and hetero...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Slugoski, Melissa D., Smith, Kyla M., Ng, Amy M. L., Yao, Sylvia Y. M., Karpinski, Edward, Cass, Carol E., Baldwin, Stephen A., Young, James D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Membrane Transport, Structure, Function, and Biogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719363/
https://ncbi.nlm.nih.gov/pubmed/19380587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009613
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky