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Substituted Cysteine Accessibility Method Analysis of Human Concentrative Nucleoside Transporter hCNT3 Reveals a Novel Discontinuous Region of Functional Importance within the CNT Family Motif (G/A)XKX(3)NEFVA(Y/M/F)

The human SLC28 family of integral membrane CNT (concentrative nucleoside transporter) proteins has three members, hCNT1, hCNT2, and hCNT3. Na(+)-coupled hCNT1 and hCNT2 transport pyrimidine and purine nucleosides, respectively, whereas hCNT3 mediates transport of both pyrimidine and purine nucleosi...

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Detalhes bibliográficos
Main Authors: Slugoski, Melissa D., Ng, Amy M. L., Yao, Sylvia Y. M., Lin, Colin C., Mulinta, Ras, Cass, Carol E., Baldwin, Stephen A., Young, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719364/
https://ncbi.nlm.nih.gov/pubmed/19380585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009704
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