Electrophysiological characterization of a recombinant human Na(+)-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes

Human concentrative nucleoside transporter 1 (hCNT1) mediates active transport of nucleosides and anticancer and antiviral nucleoside drugs across cell membranes by coupling influx to the movement of Na(+) down its electrochemical gradient. The two-microelectrode voltage-clamp technique was used to...

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Detalhes bibliográficos
Main Authors: Smith, Kyla M, Ng, Amy ML, Yao, Sylvia YM, Labedz, Kathy A, Knaus, Edward E, Wiebe, Leonard I, Cass, Carol E, Baldwin, Stephen A, Chen, Xing-Zhen, Karpinski, Edward, Young, James D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665023/
https://ncbi.nlm.nih.gov/pubmed/15194733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.068189
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