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Inward- and outward-facing homology modeling of human concentrative nucleoside transporter 3 (hCNT3) predicts an elevator-type transport mechanism

The human SLC28 family of concentrative (Na(+)-dependent) nucleoside transporters has three members, hCNT1, hCNT2 and hCNT3. Previously, we have used heterologous expression in Xenopus laevis oocytes in combination with an engineered cysteine-less hCNT3 protein hCNT3(C-) to undertake systematic subs...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Yao, Sylvia Y. M., Young, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986796/
https://ncbi.nlm.nih.gov/pubmed/30096006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2018.1506665
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