Inward- and outward-facing homology modeling of human concentrative nucleoside transporter 3 (hCNT3) predicts an elevator-type transport mechanism

The human SLC28 family of concentrative (Na(+)-dependent) nucleoside transporters has three members, hCNT1, hCNT2 and hCNT3. Previously, we have used heterologous expression in Xenopus laevis oocytes in combination with an engineered cysteine-less hCNT3 protein hCNT3(C-) to undertake systematic subs...

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發表在:Channels (Austin)
Main Authors: Yao, Sylvia Y. M., Young, James D.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2018
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986796/
https://ncbi.nlm.nih.gov/pubmed/30096006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2018.1506665
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