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Inward- and outward-facing homology modeling of human concentrative nucleoside transporter 3 (hCNT3) predicts an elevator-type transport mechanism
The human SLC28 family of concentrative (Na(+)-dependent) nucleoside transporters has three members, hCNT1, hCNT2 and hCNT3. Previously, we have used heterologous expression in Xenopus laevis oocytes in combination with an engineered cysteine-less hCNT3 protein hCNT3(C-) to undertake systematic subs...
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| Publié dans: | Channels (Austin) |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986796/ https://ncbi.nlm.nih.gov/pubmed/30096006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2018.1506665 |
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