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Phosphorylation-dependent Binding of 14-3-3 Proteins Controls TRESK Regulation

The two-pore domain K(+) channel, TRESK (TWIK-related spinal cord K(+) channel) is reversibly activated by the calcium/calmodulin-dependent protein phosphatase, calcineurin. In the present study, we report that 14-3-3 proteins directly bind to the intracellular loop of TRESK and control the kinetics...

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Sonraí Bibleagrafaíochta
Main Authors: Czirják, Gábor, Vuity, Drazsen, Enyedi, Péter
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259650/
https://ncbi.nlm.nih.gov/pubmed/18397886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800712200
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