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Phosphorylation-dependent Binding of 14-3-3 Proteins Controls TRESK Regulation
The two-pore domain K(+) channel, TRESK (TWIK-related spinal cord K(+) channel) is reversibly activated by the calcium/calmodulin-dependent protein phosphatase, calcineurin. In the present study, we report that 14-3-3 proteins directly bind to the intracellular loop of TRESK and control the kinetics...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259650/ https://ncbi.nlm.nih.gov/pubmed/18397886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800712200 |
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