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TRESK Background K(+) Channel Is Inhibited by Phosphorylation via Two Distinct Pathways
The two-pore domain K(+) channel, TRESK (TWIK-related spinal cord K(+) channel, KCNK18) is directly regulated by the calcium/calmodulin-dependent phosphatase calcineurin and 14-3-3 adaptor proteins. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3 in...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863173/ https://ncbi.nlm.nih.gov/pubmed/20215114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102020 |
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