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TRESK Background K(+) Channel Is Inhibited by Phosphorylation via Two Distinct Pathways

The two-pore domain K(+) channel, TRESK (TWIK-related spinal cord K(+) channel, KCNK18) is directly regulated by the calcium/calmodulin-dependent phosphatase calcineurin and 14-3-3 adaptor proteins. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3 in...

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書誌詳細
主要な著者: Czirják, Gábor, Enyedi, Péter
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863173/
https://ncbi.nlm.nih.gov/pubmed/20215114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102020
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