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An Obligatory Heterodimer of 14-3-3β and 14-3-3ε Is Required for Aldosterone Regulation of the Epithelial Sodium Channel
Increased distal nephron sodium absorption in response to aldosterone involves Nedd4-2 phosphorylation, which blocks its ability to ubiquitylate ENaC and increases apical membrane channel density by reducing its endocytosis. Our prior work (Liang, X., Peters, K. W., Butterworth, M. B., and Frizzell,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562081/ https://ncbi.nlm.nih.gov/pubmed/18687683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803687200 |
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