Agrin Regulation of α3 Sodium-Potassium ATPase Activity Modulates Cardiac Myocyte Contraction

Drugs that inhibit Na,K-ATPases, such as digoxin and ouabain, alter cardiac myocyte contractility. We recently demonstrated that agrin, a protein first identified at the vertebrate neuromuscular junction, binds to and regulates the activity of α3 subunit-containing isoforms of the Na,K-ATPase in the...

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Autori principali: Hilgenberg, Lutz G. W., Pham, Bryan, Ortega, Maria, Walid, Saif, Kemmerly, Thomas, O'Dowd, Diane K., Smith, Martin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Membrane Transport, Structure, Function, and Biogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719333/
https://ncbi.nlm.nih.gov/pubmed/19376779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806855200
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