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Interleukin 1α-induced NFκB Activation and Chemokine mRNA Stabilization Diverge at IRAK1
Interleukin 1α (IL-1α) is capable of driving pro-inflammatory gene expression through both the initiation of transcription and by prolonging the half-life of short-lived mRNAs. Although the signaling events linking the IL-1 receptor to the activation of NFκB and the initiation of transcription have...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259643/ https://ncbi.nlm.nih.gov/pubmed/18411265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801346200 |
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