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IL-1-induced NFκB and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK)

Mutant I1A cells, lacking IL-1 receptor-associated kinase (IRAK) mRNA and protein, have been used to study the involvement of IRAK in NFκB and c-Jun N-terminal kinase (JNK) activation. A series of IRAK deletion constructs were expressed in I1A cells, which were then tested for their ability to respo...

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Detalhes bibliográficos
Main Authors: Li, Xiaoxia, Commane, Mairead, Jiang, Zhengfan, Stark, George R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31857/
https://ncbi.nlm.nih.gov/pubmed/11287640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071054198
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