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IL-1-induced NFκB and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK)

Mutant I1A cells, lacking IL-1 receptor-associated kinase (IRAK) mRNA and protein, have been used to study the involvement of IRAK in NFκB and c-Jun N-terminal kinase (JNK) activation. A series of IRAK deletion constructs were expressed in I1A cells, which were then tested for their ability to respo...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Li, Xiaoxia, Commane, Mairead, Jiang, Zhengfan, Stark, George R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287640/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071054198
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