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Interleukin 1α-induced NFκB Activation and Chemokine mRNA Stabilization Diverge at IRAK1

Interleukin 1α (IL-1α) is capable of driving pro-inflammatory gene expression through both the initiation of transcription and by prolonging the half-life of short-lived mRNAs. Although the signaling events linking the IL-1 receptor to the activation of NFκB and the initiation of transcription have...

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Detalhes bibliográficos
Main Authors: Hartupee, Justin, Li, Xiaoxia, Hamilton, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259643/
https://ncbi.nlm.nih.gov/pubmed/18411265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801346200
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