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IL-17 signaling for mRNA stabilization does not require TRAF6

IL-17 alone is a relatively weak inducer of gene expression but cooperates with other cytokines including TNFα to generate a strong response in part via prolongation of mRNA half-life. Because TRAF6 has been reported to be essential for signaling by IL-17 we examined its involvement in IL-17-mediate...

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Detalhes bibliográficos
Main Authors: Hartupee, Justin, Liu, Caini, Novotny, Michael, Sun, Dongxu, Li, Xiaoxia, Hamilton, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665037/
https://ncbi.nlm.nih.gov/pubmed/19155515
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