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Interleukin-17 regulates CXCL1 mRNA stability via an AUUUA/Tristetraprolin-independent sequence

Interleukin (IL)-17 contributes to inflammatory response in part by promoting enhanced expression of chemokines such as CXCL1 by prolonging the half-life of this constitutively unstable mRNA. While IL-17 is a weak stimulus for transcription of the CXCL1 gene, it strongly potentiates message accumula...

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Detalhes bibliográficos
Main Authors: Datta, Shyamasree, Novotny, Michael, Pavicic, Paul G., Zhao, Chenyang, Herjan, Tomasz, Hartupee, Justin, Hamilton, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829999/
https://ncbi.nlm.nih.gov/pubmed/20042592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902423
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