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Cellular stress amplifies TLR3/4 induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1

The impact of environmental stressors on the magnitude of specific chemokine gene expression was examined in mouse bone marrow-derived macrophages stimulated through various Toll-Like Receptors (TLRs). Levels of TLR-stimulated CXCL1 and CXCL2 but not CXCL10 or CCL5 mRNAs were selectively enhanced (&...

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Detalhes bibliográficos
Main Authors: Zhao, Chenyang, Pavicic, Paul G., Datta, Shyamasree, Sun, Dongxu, Novotny, Michael, Hamilton, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091718/
https://ncbi.nlm.nih.gov/pubmed/24920846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303396
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