Modification of Drosophila p53 by SUMO Modulates Its Transactivation and Pro-apoptotic Functions

Conjugation to SUMO is a reversible post-translational modification that regulates several transcription factors involved in cell proliferation, differentiation, and disease. The p53 tumor suppressor can be modified by SUMO-1 in mammalian cells, but the functional consequences of this modification a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Mauri, Federico, McNamee, Laura M., Lunardi, Andrea, Chiacchiera, Fulvio, Del Sal, Giannino, Brodsky, Michael H., Collavin, Licio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Protein Synthesis, Post-Translational Modification, and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258953/
https://ncbi.nlm.nih.gov/pubmed/18492669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710186200
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky