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A proline-rich motif in p53 is required for transactivation- independent growth arrest as induced by Gas1

The involvement of p53 in regulating diverse cellular processes dictates that it must respond to multiple signaling mechanisms, thus coordinating the response to various “stress conditions.” Genotoxic stress has served as a paradigm to dissect the transactivation-dependent branch of the pathway by w...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ruaro, Elisabetta M., Collavin, Licio, Del Sal, Giannino, Haffner, Rebecca, Oren, Moshe, Levine, Arnold J., Schneider, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9114050/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4675
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