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Alanine Scanning of a Putative Receptor Binding Surface of Insulin-like Growth Factor-I
Current evidence supports a binding model in which the insulin molecule contains two binding surfaces, site 1 and site 2, which contact the two halves of the insulin receptor. The interaction of these two surfaces with the insulin receptor results in a high affinity cross-linking of the two receptor...
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Päätekijät: | , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Society for Biochemistry and Molecular Biology
2008
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258947/ https://ncbi.nlm.nih.gov/pubmed/18502759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802620200 |
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