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Alanine Scanning of a Putative Receptor Binding Surface of Insulin-like Growth Factor-I
Current evidence supports a binding model in which the insulin molecule contains two binding surfaces, site 1 and site 2, which contact the two halves of the insulin receptor. The interaction of these two surfaces with the insulin receptor results in a high affinity cross-linking of the two receptor...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258947/ https://ncbi.nlm.nih.gov/pubmed/18502759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802620200 |
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