Lck-dependent Fyn Activation Requires C Terminus-dependent Targeting of Kinase-active Lck to Lipid Rafts

Mechanisms regulating the activation and delivery of function of Lck and Fyn are central to the generation of the most proximal signaling events emanating from the T cell antigen receptor (TcR) complex. Recent results demonstrate that lipid rafts (LR) segregate Lck and Fyn and play a fundamental rol...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Filipp, Dominik, Moemeni, Behrouz, Ferzoco, Alessandra, Kathirkamathamby, Kirishanthy, Zhang, Jenny, Ballek, Ondřej, Davidson, Dominique, Veillette, André, Julius, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258908/
https://ncbi.nlm.nih.gov/pubmed/18660530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710372200
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares