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Lck-dependent Fyn Activation Requires C Terminus-dependent Targeting of Kinase-active Lck to Lipid Rafts

Mechanisms regulating the activation and delivery of function of Lck and Fyn are central to the generation of the most proximal signaling events emanating from the T cell antigen receptor (TcR) complex. Recent results demonstrate that lipid rafts (LR) segregate Lck and Fyn and play a fundamental rol...

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書誌詳細
主要な著者: Filipp, Dominik, Moemeni, Behrouz, Ferzoco, Alessandra, Kathirkamathamby, Kirishanthy, Zhang, Jenny, Ballek, Ondřej, Davidson, Dominique, Veillette, André, Julius, Michael
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258908/
https://ncbi.nlm.nih.gov/pubmed/18660530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710372200
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