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PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2)

Sperm-specific phospholipase C ζ (PLCζ) activates embryo development by triggering intracellular Ca(2+) oscillations in mammalian eggs indistinguishable from those at fertilization. Somatic PLC isozymes generate inositol 1,4,5-trisphophate–mediated Ca(2+) release by hydrolyzing phosphatidylinositol...

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Main Authors: Yu, Yuansong, Nomikos, Michail, Theodoridou, Maria, Nounesis, George, Lai, F. Anthony, Swann, Karl
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258180/
https://ncbi.nlm.nih.gov/pubmed/22114355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0687
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