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Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activation

A sperm-specific phospholipase C-zeta (PLCζ) is believed to play an essential role in oocyte activation during mammalian fertilization. Sperm PLCζ has been shown to trigger a prolonged series of repetitive Ca(2+) transients or oscillations in oocytes that precede activation. This remarkable intracel...

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Detalhes bibliográficos
Main Authors: Nomikos, Michail, Theodoridou, Maria, Elgmati, Khalil, Parthimos, Dimitris, Calver, Brian L., Buntwal, Luke, Nounesis, George, Swann, Karl, Lai, F. Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023910/
https://ncbi.nlm.nih.gov/pubmed/24478462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gau011
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