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RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage

RNA-binding protein HuR modulates the stability and translational efficiency of messenger RNAs (mRNAs) encoding essential components of the cellular proliferation, growth and survival pathways. Consistent with these functions, HuR levels are often elevated in cancer cells and reduced in senescent an...

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Autors principals: Dai, Weijun, Zhang, Gen, Makeyev, Eugene V.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258158/
https://ncbi.nlm.nih.gov/pubmed/21948791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr783
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