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RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage
RNA-binding protein HuR modulates the stability and translational efficiency of messenger RNAs (mRNAs) encoding essential components of the cellular proliferation, growth and survival pathways. Consistent with these functions, HuR levels are often elevated in cancer cells and reduced in senescent an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258158/ https://ncbi.nlm.nih.gov/pubmed/21948791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr783 |
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