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The identification of an endonuclease that cleaves within an HuR binding site in mRNA

Messenger RNAs (mRNAs) that contain U-rich elements are targeted for rapid decay. Selective inhibition of this decay results in a rapid increase in steady state level. Thus, this is an important regulatory step in gene expression. Previously, we have found that these mRNAs are selectively stabilized...

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Bibliografiske detaljer
Main Authors: Zhao, Zhiquan, Chang, Feng-Ching, Furneaux, Henry M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102663/
https://ncbi.nlm.nih.gov/pubmed/10908325
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