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The identification of an endonuclease that cleaves within an HuR binding site in mRNA

Messenger RNAs (mRNAs) that contain U-rich elements are targeted for rapid decay. Selective inhibition of this decay results in a rapid increase in steady state level. Thus, this is an important regulatory step in gene expression. Previously, we have found that these mRNAs are selectively stabilized...

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Pubblicato in:Nucleic Acids Res
Autori principali: Zhao, Zhiquan, Chang, Feng-Ching, Furneaux, Henry M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.14.2695
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